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Crystal Structure of SARS-CoV-2 Nucleocapsid Protein RNA Binding Domain Reveals Potential Unique Drug Targeting Sites

October 22, 2020
Mindzilla

County Clare, Ireland — The outbreak of coronavirus disease (COVID-19) caused by SARS-CoV-2 virus continues to cause human infection and mortality worldwide. Currently, there are no specific viral...

Researchers Discovered the Second ‘Key’ Used by the SARS-CoV-2 Virus to Enter into Human Cells

October 22, 2020
Mindzilla

Helsinki, Finland — To efficiently infect human cells, SARS-CoV-2, the virus that causes COVID-19, is able to use a receptor called Neuropilin-1, which is very abundant in many human tissues including...

AI Methods of Analyzing Social Networks Find New Cell Types in Tissue

October 22, 2020
Mindzilla

Uppsala, Sweden — In situ sequencing enables gene activity inside body tissues to be depicted in microscope images. To facilitate interpretation of the vast quantities of information generated, Uppsala...

Hand-Held Device Reads Levels of Cancer Biomarker

October 22, 2020
Mindzilla

Hamilton, ON — Researchers at McMaster and Brock universities have created the prototype for a hand-held device to measure a biomarker for cancer, paving the way for home-based cancer monitoring and...

Study Identifies Key Enzyme for Development of Autoimmune Diseases

October 22, 2020
Mindzilla

São Paulo, Brazil — Scientists affiliated with the Center for Research on Inflammatory Diseases, hosted by the University of São Paulo (USP) in Brazil, have discovered that an enzyme involved in key...

Study Reveals Restoration of Retinal and Visual Function Following Gene Therapy

October 20, 2020
Mindzilla

Irvine, CA — A breakthrough study, led by researchers from the University of California, Irvine, results in the restoration of retinal and visual functions of mice models suffering from inherited retinal...

Fats Fighting Back Against Bacteria

October 20, 2020
Mindzilla

Queensland, Australia — Droplets of fat inside our cells are helping the body’s own defence system fight back against infection, University of Queenslandresearchers have discovered. The international...

Gel Instrumental in 3D Bioprinting Biological Tissues

October 20, 2020
Mindzilla

State College, PA — The eventual creation of replacement biological parts requires fully three-dimensional capabilities that two-dimensional and three-dimensional thin-film bioprinting cannot supply....

New Strategy for siRNA Stabilization by Artificial Cationic Oligosaccharide

October 20, 2020
Mindzilla

Tokyo, Japan — RNA interference is a gene regulatory mechanism in which the expression of specific genes is downregulated by endogenous microRNAs or by small interfering RNAs (siRNAs). Although siRNAs...

Peptides+Antibiotic Combination may Result in a More Effective Treatment for Leishmaniasis

October 20, 2020
Mindzilla

Barcelona, Spain — Leishmaniasis is caused by the protozoan Leishmania parasites which are transmitted by the bite of an infected sandfly. Although in rich countries this disease mainly affects dogs,...

Viral ‘Molecular Scissor’ is Next COVID-19 Drug Target

October 20, 2020
Mindzilla

San Antonio, TX — American and Polish scientists, reporting Oct. 16 in the journal Science Advances, laid out a novel rationale for COVID-19 drug design – blocking a molecular “scissor”...

Discoveries Suggest New Breast Cancer Treatment

October 19, 2020
Mindzilla

Melbourne, Australia — Findings by Monash Biomedicine Discovery Institute (BDI) researchers have pointed to a new combination of treatments that may help breast cancer patients with certain gene mutations. The...

Scientists Propose Potential Method for Imaging-Guided Synergistic Cancer Therapy

October 19, 2020
Mindzilla

Beijing, China — A joint research team led by Prof. WANG Hui and Prof. LIN Wenchu from the High Magnetic Field Laboratory of the Hefei Institutes of Physical Science developed a synthesis of metal-free...

Small RNA as a Central Player in Infections

October 19, 2020
Mindzilla

Würzburg, Germany — More than half of the world’s population carries the bacterium Helicobacter pylori in their stomach mucosa. It often causes no problems throughout life, but sometimes it can...

Novel Antiviral Strategy for Treatment of COVID-19

October 19, 2020
Mindzilla

Hong Kong, China — A research team led by Professor Hongzhe SUN, Norman & Cecilia Yip Professor in Bioinorganic Chemistry, Department of Chemistry, Faculty of Science, and Professor Kwok Yung YUEN,...

Study Reveals Most Effective Drugs for Common Type of Neuropathic Pain

October 19, 2020
Mindzilla

Columbia, MO — More than 20 million people in the U.S. suffer neuropathic pain. At least 25% of those cases are classified as unexplained and considered cryptogenic sensory polyneuropathy (CSPN). There...

New Test can Target and Capture Most Lethal Cells in Fatal Brain Cancer

October 19, 2020
Mindzilla

Baltimore, MD — A laboratory test developed by a research team led by Johns Hopkins University bioengineers can accurately pinpoint, capture and analyze the deadliest cells in the most common and aggressive...

New Technology Diagnoses Sickle Cell Disease in Record Time

October 19, 2020
Mindzilla

Boulder, CO — Researchers at the University of Colorado Boulder and the University of Colorado Anschutz Medical Campus have developed a new way to diagnose diseases of the blood like sickle cell disease...

Researchers Make Counterintuitive Discoveries About Immune-Like Characteristics of Cells

October 19, 2020
Mindzilla

Nashville, TN — Vanderbilt University researchers have reported the counterintuitive discovery that certain chemotherapeutic agents used to treat tumours can have the opposite effect of tissue overgrowth...

An Alternative to Animal Experiments

October 15, 2020
Mindzilla

Munich, Germany — The human intestine is vital for both digestion and absorbing nutrients as well as drugs. For any type of research that involves intestines, scientists require research models that...

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