Mindzilla – Drug Development

Drug Development

Common Bacteria Modified to Make Designer Sugar-Based Drug

March 3, 2021
Mindzilla

Troy, NY — Envisioning an animal-free drug supply, scientists have — for the first time — reprogrammed a common bacterium to make a designer polysaccharide molecule used in pharmaceuticals...

Research Team Develops Dual-Targeting Drug for EBV-Related Cancers

March 3, 2021
Mindzilla

Hong Kong, China — A Hong Kong Baptist University-led (HKBU) research team has developed a novel drug which has the potential to become a next-generation treatment for cancers associated with Epstein-Barr...

New Substance to Suppress Neuroinflammation

March 1, 2021
Mindzilla

Moscow, Russia — Biologists from RUDN University confirmed that a well-known spasmolytic drug called hymecromone can suppress the inflammatory response in astrocytes, important glial cells of the central...

Research Team identifies potential drug to treat SARS-CoV-2

February 23, 2021
Mindzilla

College Station, TX — A federally approved heart medication shows significant effectiveness in interfering with SARS-CoV-2 entry into the human cell host, according to a new study by a research team...

Insights into the role of DNA repair and Huntington’s disease gene mutation open new avenues for drug discovery

February 12, 2021
Mindzilla

Amsterdam, Netherlands — Recent genetic data from patients with Huntington’s disease (HD) show that DNA repair is an important factor that determines how early or late the disease occurs in individuals...

STINGing Tumours with Nanoparticles

February 9, 2021
Mindzilla

Dallas, TX — A new nanoparticle-based drug can boost the body’s innate immune system and make it more effective at fighting off tumours, researchers at UT Southwestern have shown. Their study,...

Drug for Rare Disorder Shows Promise for Treating Herpes Viruses

December 8, 2020
Mindzilla

Chicago, IL — A drug currently prescribed to treat a rare enzyme deficiency can help cells clear the herpes simplex 1 and herpes simplex 2 viruses, according to a new study published in the journal Science...

Drug Aprotinin Inhibits Entry of SARS-CoV2 in Host Cells

November 24, 2020
Mindzilla

Frankfurt, Germany — The surface of the SARS-CoV-2 virus is studded with spike proteins. The virus needs these in order to dock onto proteins (ACE2 receptors) on the surface of the host cell. Before...

Insights in the Search for New Antibiotics

November 20, 2020
Mindzilla

Norman, OK — A collaborative research team from the University of Oklahoma, the Memorial Sloan Kettering Cancer Center and Merck & Co. published an opinion article in the journal, Nature Chemical...

Comprehensive Safety Testing of COVID-19 Vaccines Based on Experience with Prior Vaccines

November 19, 2020
Mindzilla

Washington, DC — “The urgent need for COVID-19 vaccines must be balanced with the imperative of ensuring safety and public confidence in vaccines by following the established clinical safety...

New Drug for HCM Reduces Heart Mass

November 17, 2020
Mindzilla

Ann Arbor, MI — For the first time, a medication has impacted heart muscle thickness and function for patients with the most common inherited heart condition, rather than simply addressing their symptoms. “This...

Two Anti-Inflammatory Compounds Shown to be Capable of Accelerating Recovery from COVID-19

November 16, 2020
Mindzilla

São Paulo, Brazil — Two independent clinical studies – one by researchers at the Center for Cell-Based Therapy (CTC) in Ribeirão Preto, state of São Paulo (Brazil), on the monoclonal antibody eculizumab,...

Study Reveals Strategy to Create COVID-19 Drugs to Inhibit Virus’s Entry and Replication

November 6, 2020
Mindzilla

Tampa FL — SARS-CoV-2, the respiratory virus that causes COVID-19, attacks the body in multiple steps. Gaining entry into cells deep within the lungs and hijacking the human host cell’s machinery...

Viral ‘Molecular Scissor’ is Next COVID-19 Drug Target

October 20, 2020
Mindzilla

San Antonio, TX — American and Polish scientists, reporting Oct. 16 in the journal Science Advances, laid out a novel rationale for COVID-19 drug design – blocking a molecular “scissor”...

Novel Antiviral Strategy for Treatment of COVID-19

October 19, 2020
Mindzilla

Hong Kong, China — A research team led by Professor Hongzhe SUN, Norman & Cecilia Yip Professor in Bioinorganic Chemistry, Department of Chemistry, Faculty of Science, and Professor Kwok Yung YUEN,...

Scientists Develop New Precise Therapeutic Leukaemia Vaccine

October 13, 2020
Mindzilla

Beijing, China — Exploration of new leukaemia antigens and construction of appropriate delivery systems using FDA-approved material are important strategies for developing leukaemia vaccines for clinic...

Anti-Convulsant Drug can Modify DNA Conformation and Interact with Chromosome Proteins

September 29, 2020
Mindzilla

São Paulo, Brazil — Results of recent studies involving valproic acid, used for decades as an anti-convulsant drug, show that it can interact with the conformation of DNA and regulate gene expression. These...

Attacking Tumours from the Inside

September 7, 2020
Mindzilla

Dallas, TX — A new technology that allows researchers to peer inside malignant tumours shows that two experimental drugs can normalize aberrant blood vessels, oxygenation, and other aspects of the...

New Syringe Technology could Enable Injection of Highly Concentrated Biologic Drugs

August 25, 2020
Mindzilla

Cambridge, MA — MIT researchers have developed a simple, low-cost technology to administer powerful drug formulations that are too viscous to be injected using conventional medical syringes. The...

Developing Precise Medicines for Triple Negative Breast Cancer

August 25, 2020
Mindzilla

Toronto, Canada — Taking advantage of a cancer cell’s altered metabolism that drives its runaway growth, Princess Margaret researchers are zeroing in on these molecular changes to help them develop...

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