Mindzilla – Drug Development

Drug Development

Chemists Propose a One-Step Synthesis of Substances for Medicine

July 19, 2021
Mindzilla

Moscow, Russia — The RUDN University chemists have discovered a reaction for the synthesis of acetimidamides, heterocyclic compounds with biological activity that can be used for the synthesis of hormones,...

‘Unexciting’ an Anxious Brain: Novel Drug Reduces Anxiety-like Behaviour in Mice

June 30, 2021
Mindzilla

Tokyo, Japan — Anxiety, commonly termed as a feeling of fear, dread, and restlessness, is a perfectly normal reaction to stressful situations. However, a state of heightened anxiety, which is the reality...

New Drug-Formulation Method may Lead to Smaller Pills

June 8, 2021
Mindzilla

Cambridge, MA — About 60 percent of drugs on the market have hydrophobic molecules as their active ingredients. These drugs, which are not soluble in water, can be difficult to formulate into tablets...

Drug Development Platform could Provide Flexible, Rapid and Targeted Antimicrobials

April 21, 2021
Mindzilla

Boulder, CO — When disease outbreaks happen, response time in developing and distributing treatments is crucial to saving lives. Unfortunately, developing custom drugs as countermeasures is often a...

Designing Better Antibody Drugs with Artificial Intelligence

April 16, 2021
Mindzilla

Zürich, Switzerland — Antibodies are not only produced by our immune cells to fight viruses and other pathogens in the body. For a few decades now, medicine has also been using antibodies produced...

Anti-Inflammatory Drug Protects Against Lethal Inflammation from COVID-19 in Animal Models

April 1, 2021
Mindzilla

New York, NY — Mount Sinai researchers have found that a widely available and inexpensive drug targeting inflammatory genes has reduced morbidity and mortality in mice infected with SARS-CoV-2, the...

Chemists Achieve Breakthrough in Production of 3D Molecular Structures

March 26, 2021
Mindzilla

Münster, Germany — A major goal of organic and medicinal chemistry in recent decades has been the rapid synthesis of three-dimensional molecules for the development of new drugs. These drug candidates...

Focusing on the Unhealthy Brain to Speed Drug Discovery

March 23, 2021
Mindzilla

Houston, TX — Though 40 million concussions are recorded annually, no effective treatment exists for them or for many other brain-related illnesses. In collaboration with Dragan Maric of the National...

Faster Drug Discovery Through Machine Learning

March 16, 2021
Mindzilla

Cambridge, MA — Drugs can only work if they stick to their target proteins in the body. Assessing that stickiness is a key hurdle in the drug discovery and screening process. New research combining...

Common Bacteria Modified to Make Designer Sugar-Based Drug

March 3, 2021
Mindzilla

Troy, NY — Envisioning an animal-free drug supply, scientists have — for the first time — reprogrammed a common bacterium to make a designer polysaccharide molecule used in pharmaceuticals...

Research Team Develops Dual-Targeting Drug for EBV-Related Cancers

March 3, 2021
Mindzilla

Hong Kong, China — A Hong Kong Baptist University-led (HKBU) research team has developed a novel drug which has the potential to become a next-generation treatment for cancers associated with Epstein-Barr...

New Substance to Suppress Neuroinflammation

March 1, 2021
Mindzilla

Moscow, Russia — Biologists from RUDN University confirmed that a well-known spasmolytic drug called hymecromone can suppress the inflammatory response in astrocytes, important glial cells of the central...

Research Team identifies potential drug to treat SARS-CoV-2

February 23, 2021
Mindzilla

College Station, TX — A federally approved heart medication shows significant effectiveness in interfering with SARS-CoV-2 entry into the human cell host, according to a new study by a research team...

Insights into the role of DNA repair and Huntington’s disease gene mutation open new avenues for drug discovery

February 12, 2021
Mindzilla

Amsterdam, Netherlands — Recent genetic data from patients with Huntington’s disease (HD) show that DNA repair is an important factor that determines how early or late the disease occurs in individuals...

STINGing Tumours with Nanoparticles

February 9, 2021
Mindzilla

Dallas, TX — A new nanoparticle-based drug can boost the body’s innate immune system and make it more effective at fighting off tumours, researchers at UT Southwestern have shown. Their study,...

Drug for Rare Disorder Shows Promise for Treating Herpes Viruses

December 8, 2020
Mindzilla

Chicago, IL — A drug currently prescribed to treat a rare enzyme deficiency can help cells clear the herpes simplex 1 and herpes simplex 2 viruses, according to a new study published in the journal Science...

Drug Aprotinin Inhibits Entry of SARS-CoV2 in Host Cells

November 24, 2020
Mindzilla

Frankfurt, Germany — The surface of the SARS-CoV-2 virus is studded with spike proteins. The virus needs these in order to dock onto proteins (ACE2 receptors) on the surface of the host cell. Before...

Insights in the Search for New Antibiotics

November 20, 2020
Mindzilla

Norman, OK — A collaborative research team from the University of Oklahoma, the Memorial Sloan Kettering Cancer Center and Merck & Co. published an opinion article in the journal, Nature Chemical...

Comprehensive Safety Testing of COVID-19 Vaccines Based on Experience with Prior Vaccines

November 19, 2020
Mindzilla

Washington, DC — “The urgent need for COVID-19 vaccines must be balanced with the imperative of ensuring safety and public confidence in vaccines by following the established clinical safety...

New Drug for HCM Reduces Heart Mass

November 17, 2020
Mindzilla

Ann Arbor, MI — For the first time, a medication has impacted heart muscle thickness and function for patients with the most common inherited heart condition, rather than simply addressing their symptoms. “This...

T&C

Privacy