Mindzilla – Genomics

Genomics

No IgA Leads to Intestinal Inflammation in Mice

July 23, 2021
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Tokyo, Japan — While researchers have known for years that immunoglobulin A (IgA) is important for gut health, it has remained unclear exactly what role it plays in preventing infection and disease....

New Discoveries Reveal How Aacute Myeloid Leukaemia Walks Line Between Growth and Cell Death

July 23, 2021
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Chicago, IL — Researchers revealed new insights into how acute myeloid leukemia (AML) develops and progresses, according to a study published in Molecular Cell on July 20, 2021. They describe a mechanism...

Championing Chrononutrition with Protein, the Morning Elixir for Muscle Growth

July 22, 2021
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Tokyo, Japan — Proteins constitute an essential dietary component that help in the growth and repair of the body. Composed of long chains of amino acids, proteins promote the growth of skeletal muscles,...

DNA Duplication Linked to the Origin and Evolution of Pine Trees and Their Relatives

July 22, 2021
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Gainesville, FL — Plants are DNA hoarders. Adhering to the maxim of never throwing anything out that might be useful later, they often duplicate their entire genome and hang on to the added genetic...

RNA Modification may Protect Against Liver Disease

July 22, 2021
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Los Angeles, CA — A chemical modification that occurs in some RNA molecules as they carry genetic instructions from DNA to cells’ protein-making machinery may offer protection against non-alcoholic...

New Model can Predict Multiple RNA Modifications Simultaneously

July 22, 2021
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Suzhou, China — The ability to predict and interpret modifications of ribonucleic acid (RNA) has been a welcome advance in biochemistry research. However, existing predictive approaches have a...

Researchers Find New Protein Conducting piRNA Expression

July 19, 2021
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Hefei, China — PIWI-interacting RNAs (piRNAs), a class of conserved non-coding small RNAs, are essential for sex determination, defense against viruses, maintaining genome integrity of diverse animal...

The Virus Trap

July 19, 2021
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Munich, Germany — To date, there are no effective antidotes against most virus infections. An interdisciplinary research team at the Technical University of Munich (TUM) has now developed a new approach:...

Genome Studies: More is Not Always Better

July 16, 2021
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Würzburg, Germany — What the fruit fly is to zoologists, the thale cress is to botanists. The widespread herb with the botanical name Arabidopsis thaliana serves them as a model organism from which...

Preventing Lung Cancer’s Unwelcome Return

July 15, 2021
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Cold Spring Harbor, NY — When a doctor gives a patient antibiotics for a bacterial infection, they usually require them to finish the entire treatment, even when symptoms go away. This is to ensure...

Innovative Gene Therapy ‘Reprograms’ Cells to Reverse Neurological Deficiencies

July 14, 2021
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Columbus, OH — A novel method of gene therapy is helping children born with a rare genetic disorder called AADC deficiency that causes severe physical and developmental disabilities. The study, led...

Path(way) Less Traveled in DNA Double-Strand Break Repair

July 14, 2021
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Osaka, Japan — BRCA1, a protein that is well-known for its role in hereditary breast cancer, is an important part of the cellular system that repairs double-strand DNA breaks. Now, researchers from...

Researchers Discover New Pathway to Tackle Follicular Lymphoma

July 14, 2021
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Madrid, Spain — For their own benefit and to grow beyond control, tumours manipulate cell signals to make it appear as if the cells have the nutrients they need. That is the case in follicular lymphoma,...

The Equalizer: An Engineered Circuit for Uniform Gene Expression

July 13, 2021
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Houston, TX — The function of a protein can depend on its abundance in a cell. So, when investigating the properties of a new protein, it is essential to make sure that the same amount is produced...

Match Matters: The Right Combination of Parents can Turn a Gene Off Indefinitely

July 13, 2021
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College Park, MD — Evidence suggests that what happens in one generation–diet, toxin exposure, trauma, fear–can have lasting effects on future generations. Scientists believe these effects...

Biosynthesis Pathway of a New DNA Nucleobase Elucidated

July 12, 2021
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Paris, France — DNA is composed of nucleobases represented by the letters A, T, G and C. They form the basis of the genetic code and are present in all living beings. But in a bacteriophage, another...

Where Does the Shape of the Romanesco Cauliflower Come from?

July 12, 2021
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Paris, France — The mystery of the formation of one of the most peculiar plant forms – the Romanesco cauliflower – has been solved by a team of scientists from the CNRS1 and Inria in an...

Relationship between Chromosomal Instability and Senescence Revealed in Fly Drosophila

July 9, 2021
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Barcelona, Spain — Chromosomal instability is a feature of solid tumours such as carcinoma. Likewise, cellular senescence is a process that is highly related to cellular ageing and its link to cancer...

Making Sense of Antisense Gene Silencing

July 8, 2021
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Tokyo, Japan — Researchers from Tokyo Medical and Dental University (TMDU) find proteins that bind to and regulate tocopherol-conjugated heteroduplex oligonucleotides during gene silencing Gene...

Memory Making Involves Extensive DNA Breaking

July 8, 2021
Mindzilla

Cambridge, MA — The urgency to remember a dangerous experience requires the brain to make a series of potentially dangerous moves: Neurons and other brain cells snap open their DNA in numerous locations–more...

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