Mindzilla – Genomics

Genomics

The Road to Uncovering a Novel Mechanism for Disposing of Misfolded Proteins

October 22, 2020
Mindzilla

Houston, TX — About 30 years ago, Dr. Richard Sifers set out on a journey to discover why people with a rare condition known as alpha1-antitrypsin (AAT) deficiency present with high variation in the...

AI Methods of Analyzing Social Networks Find New Cell Types in Tissue

October 22, 2020
Mindzilla

Uppsala, Sweden — In situ sequencing enables gene activity inside body tissues to be depicted in microscope images. To facilitate interpretation of the vast quantities of information generated, Uppsala...

‘Multi-Omics’ Adds New Cell to Immune Family Tree

October 22, 2020
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Parkville, Australia — WEHI researchers have used powerful ‘single cell multi-omics’ technologies to discover a previously unknown ancestor of T and B lymphocytes, which are critical components...

Study Discovers Gene that Helps Us Know When It’s Time to Urinate

October 20, 2020
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La Jolla, CA — In a National Institutes of Health (NIH)-funded study involving both mice and patients who are part of an NIH Clinical Center trial, researchers discovered that a gene, called PIEZO2,...

Study Reveals Restoration of Retinal and Visual Function Following Gene Therapy

October 20, 2020
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Irvine, CA — A breakthrough study, led by researchers from the University of California, Irvine, results in the restoration of retinal and visual functions of mice models suffering from inherited retinal...

Lineage Tracing of Direct Astrocyte-to-Neuron Conversion for Brain Repair

October 20, 2020
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Guangzhou, China — Regeneration of functional new neurons to repair injured human brain is a long-term unsolved problem up till today. The lack of neuroregeneration is one of the major reasons why...

Discoveries Suggest New Breast Cancer Treatment

October 19, 2020
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Melbourne, Australia — Findings by Monash Biomedicine Discovery Institute (BDI) researchers have pointed to a new combination of treatments that may help breast cancer patients with certain gene mutations. The...

Small RNA as a Central Player in Infections

October 19, 2020
Mindzilla

Würzburg, Germany — More than half of the world’s population carries the bacterium Helicobacter pylori in their stomach mucosa. It often causes no problems throughout life, but sometimes it can...

Rare Congenital Heart Defect Rescued by Protease Inhibition

October 19, 2020
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Greenwood, SC — A research team at the Greenwood Genetic Center (GGC) has successfully used small molecules to restore normal heart and valve development in an animal model for Mucolipidosis II (ML...

Researchers Mine Data and Connect the Dots About Processes Driving Neuroblastoma

October 15, 2020
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Memphis, TN — Researchers have used insight from a comprehensive genomic analysis of neuroblastoma to learn about the process driving one of the most common childhood solid tumours. The findings revealed...

Protein that Keeps Immune System from Freaking Out could Form Basis for New Therapeutics

October 15, 2020
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La Jolla, CA — The immune response to infections is a delicate balance. We need just enough action to clear away the offending bacteria or viruses, but not so much that our own bodies suffer collateral...

Technique to Recover Lost Single-Cell RNA-Sequencing Information

October 15, 2020
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Cambridge, MA — Sequencing RNA from individual cells can reveal a great deal of information about what those cells are doing in the body. MIT researchers have now greatly boosted the amount of information...

World First Study Shows Some Microorganisms can Bend the Rules of Evolution

October 15, 2020
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Melbourne, Australia — In a world first Monash University scientists have discovered that HGT can bend the rules of evolution. The discovery is outlined in a study published today in PNAS, which...

Single Gene Disorders not so Simple After All

October 13, 2020
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Chicago, IL — Traditionally, geneticists divide disorders into “simple,” where a single gene mutation causes disease, or complex, where mutations in many genes contribute modest amounts....

Novel Map Reveals How Immune Cells Fight and Remember Infections

October 13, 2020
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Hinxton, UK — Researchers have charted the activity of tens of thousands of genes in mouse immune cells over the course of an infection. The study from the University of Melbourne, Australia, the Wellcome...

When It Comes to Arthritic Bone Spurs, Stem Cells Hurt Instead of Heal

October 12, 2020
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Los Angeles, CA — The same stem cells that heal broken bones can also generate arthritic bone spurs called osteophytes, according to a new study in the Annals of the Rheumatic Diseases. “Although...

Terahertz Zaps Alter Gene Activity in Stem Cells

October 12, 2020
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Kyoto, Japan — Terahertz light pulses change gene expression in stem cells, report researchers from Kyoto University’s Institute for Integrated Cell-Material Sciences (iCeMS) and Tokai University...

Reprogram CRISPR System in Mice to Eliminate Tumour Cells Without Affecting Healthy Cells

October 12, 2020
Mindzilla

Madrid, Spain — The CRISPR/Cas9 gene-editing tool is one of the most promising approaches to advancing treatments of genetic diseases – including cancer -, an area of research where progress...

New Assembler for Decoding Genomes of Microbial Communities Developed

October 12, 2020
Mindzilla

St Petersburg, Russia — Researchers from the Center for Algorithmic Biotechnology at St Petersburg University, as part of a group of Russian and American scientists, have developed the metaFlye assembler....

Alzheimer’s Risk Gene Disrupts Endocytosis, but Another Disease-Linked Gene could Help

October 8, 2020
Mindzilla

Cambridge, MA — In a new study, a team of scientists based at The Picower Institute for Learning and Memory at MIT and the Whitehead Institute for Biomedical Research reveals evidence showing that...

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