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The Architect of Genome Folding

April 15, 2021
Mindzilla

Halle (Saale), Germany — The DNA molecule is not naked in the nucleus. Instead, it is folded in a very organized way by the help of different proteins to establish a unique spatial organization of...

Self-Assembling Nanofibers Prevent Damage from Inflammation

April 15, 2021
Mindzilla

Durham, NC — Biomedical engineers at Duke University have developed a self-assembling nanomaterial that can help limit damage caused by inflammatory diseases by activating key cells in the immune system....

DNA Structure Itself is Involved in Genome Regulation

April 15, 2021
Mindzilla

Madrid, Spain — The (when stretched) two-metre-long DNA molecule in each human cell is continuously being unpacked and packed again to enable the expression of genetic information. When genes must...

Aged Bone Marrow Niche Impedes Function of Rejuvenated Hematopoietic Stem Cells

April 15, 2021
Mindzilla

Durham, NC — When leukaemia strikes an older person, it is in part due to the aging of his or her hematopoietic stem cells (HSCs). These immature cells can develop into all types of blood cells, including...

Superbug Killer: New Nanotech Destroys Bacteria and Fungal Cells

April 15, 2021
Mindzilla

Melbourne, Australia — Researchers have developed a new superbug-destroying coating that could be used on wound dressings and implants to prevent and treat potentially deadly bacterial and fungal infections. The...

Researchers Establish Intracellular Interaction Network in Breast Cancer

April 15, 2021
Mindzilla

Moscow, Russia — Researchers at HSE University have identified the genes that play a crucial role in breast cancer metastasis. The results of the study were published in the journal PLOS ONE. Every...

Lab Study Solves Textbook Problem: How Cells Know Their Size

April 15, 2021
Mindzilla

Hanover, NH — Scientists have searched for years to understand how cells measure their size. Cell size is critical. It’s what regulates cell division in a growing organism. When the microscopic...

Protein can Release Trapped Histones in the Cell

April 15, 2021
Mindzilla

Copenhagen, Denmark — In the cell nucleus histones play a crucial role packaging DNA into chromatin. Histones are however very sticky to both DNA and RNA, so to ensure they are transported to the cell...

Inside the Protein Channel that Keeps Bacteria Alive

April 14, 2021
Mindzilla

New York, NY — Almost all bacteria rely on the same emergency valves–protein channels that pop open under pressure, releasing a deluge of cell contents. It is a last-ditch effort, a failsafe...

Researchers Discover New Way to Monitor & Prevent Nerve Cell Deterioration After TBI

April 14, 2021
Mindzilla

Cleveland, OH — Violent blows or jolts to the head can cause traumatic brain injury (TBI), and there are currently about five million people in the U.S. living with some form of chronic impairment...

Chemical Modification of RNA could Play Key Role in Polycystic Kidney Disease

April 14, 2021
Mindzilla

Dallas, TX — A chemical modification of RNA that can be influenced by diet appears to play a key role in polycystic kidney disease, an inherited disorder that is the fourth leading cause of kidney...

For Tomato Genes, One Plus One Doesn’t Always Make Two

April 14, 2021
Mindzilla

Cold Spring Harbor, NY — Both people and tomatoes come in different shapes and sizes. That is because every individual has a unique set of genetic variations–mutations–that affect how genes...

Cancer DNA Blood Tests Validated by International Research Team

April 14, 2021
Mindzilla

Darlinghurst, Australia — An international team today reports the findings of an independent assessment of five commercially-available assays for tumour DNA sequencing – a fast, cheap and less...

Gut Epithelium Muscles Up Against Infection

April 14, 2021
Mindzilla

Uppsala, Sweden — To maximise absorption of nutrients from the diet, the intestinal mucous membrane has a large surface area. However, this also makes it vulnerable to attack from aggressive gut microbes....

Tummy Invader: This Bacterial Molecule may be Key to Fighting Stomach Cancer

April 13, 2021
Mindzilla

Osaka, Japan — Humans are exposed to many types of bacteria daily, the majority of which are harmless. However, some bacteria are pathogenic, which means they can cause disease. An extremely common...

More than the Sum of Mutations

April 13, 2021
Mindzilla

Halle (Saale), Germany — A new algorithm can predict which genes cause cancer, even if their DNA sequence is not changed. A team of researchers in Berlin combined a wide variety of data, analyzed it...

Brain Damage Caused by Plasticisers

April 13, 2021
Mindzilla

Bayreuth, Germany — The plasticisers contained in many everyday objects can impair important brain functions in humans. Biologists from the University of Bayreuth warn of this danger in an article...

Technique Allows Mapping of Epigenetic Information in Single Cells at Scale

April 13, 2021
Mindzilla

Solna, Sweden — Histones are tiny proteins that bind to DNA and hold information that can help turn on or off individual genes. Researchers at Karolinska Institutet have developed a technique that...

Neural Stem Cells Age Rapidly, Study Reveals

April 13, 2021
Mindzilla

Los Angeles, CA — In a new study published in Cell Stem Cell, a team led by USC Stem Cell scientist Dr. Michael Bonaguidi, demonstrates that neural stem cells – the stem cells of the nervous...

Activating the Brain’s Immune System Against Cancer Prevents It from Spreading

April 13, 2021
Mindzilla

Tel Aviv-Yafo, Israel — Groundbreaking research from Tel Aviv University may lead to a significant breakthrough in the battle against deadly brain cancer. To begin with, the researchers identified...

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