Mindzilla – Proteomics

Proteomics

Proteins in Motion

November 23, 2020
Mindzilla

München, Germany — Proteins are the essential substrate of learning and memory. However, while memories can last a life-time, proteins are relatively short-lived molecules that need to be replenished...

Study Pinpoints Target for Managing Inflammation, Promoting Tissue Repair

November 17, 2020
Mindzilla

Cincinnati, OH — Managing the activity of the BCAP protein could help the body repair intestinal tissue from damage caused by inflammation, according to a new study led by experts at Cincinnati Children’s. The...

Researchers Identify Promising New Compounds to Potentially Treat Novel Coronaviruses

November 16, 2020
Mindzilla

Baltimore, MD — Researchers at the University of Maryland School of Medicine (UMSOM) and School of Pharmacy (UMSOP) have discovered new drug compounds to potentially treat the novel coronavirus that...

Examining Impact of a Point Mutation in SARS-Cov-2 Spike on Virus Transmission and Pathogenicity

November 13, 2020
Mindzilla

Washington, DC — The current dominant variant of SARS-CoV-2, containing a D614G substitution in the spike protein, appears to have evolved to enhance transmissibility, according to a new study in human...

‘BAH-Code’ Reader Senses Gene-Silencing Tag in Cells

November 3, 2020
Mindzilla

Chapel Hill, N.C. — University of North Carolina Lineberger Comprehensive Cancer Center researchers have identified a new and evolutionarily conserved pathway responsible for “closing down”...

Protein Dress of a Neuron

November 3, 2020
Mindzilla

München, Germany — Where in a nerve cell is a certain receptor protein located? Without an answer to this question, it is difficult to draw firm conclusions about the function of this protein. Two...

Discovery of pH-Dependent ‘Switch’ in Interaction Between Pair of Protein Molecules

October 27, 2020
Mindzilla

Beijing, China — All biological processes are in some way pH-dependent. Our human bodies, and those of other organisms, need to maintain specific- and constant- pH regulation in order to function....

Hidden States of the COVID-19 Spike Protein

October 26, 2020
Mindzilla

Austin, TX — The virus wreaking havoc on our lives is an efficient infection machine. Comprised of only 29 proteins (compared to our 400,000), with a genome 1/200,000 the size of ours, SARS-CoV-2 is...

The Road to Uncovering a Novel Mechanism for Disposing of Misfolded Proteins

October 22, 2020
Mindzilla

Houston, TX — About 30 years ago, Dr. Richard Sifers set out on a journey to discover why people with a rare condition known as alpha1-antitrypsin (AAT) deficiency present with high variation in the...

Duelling Proteins Give Shape to Plants

October 13, 2020
Mindzilla

Philadelphia, PA — In an elegant choreography, plants take cues from their environment and channel them into flowers, roots, or branches. In a new paper in Nature Communications, biologist Doris Wagner...

Inhibiting Epileptic Activity in the Brain

October 12, 2020
Mindzilla

Chicago, IL — Epileptic seizures often originate in small, localized areas of the brain where neurons abnormally fire in unison. These electrical impulses disrupt proper brain functioning and cause...

Taking Sides – Factors that Influence Patterns in Protein Distribution

October 12, 2020
Mindzilla

Norwich, UK — In plants, many proteins are found at only one end of a cell, giving them a polarity like heads and tails on a coin. Often, cells next to each other have these proteins at the same...

Researchers Discover a Novel Family of Toxins Used in Bacterial Competition

September 22, 2020
Mindzilla

São Paulo, Brazil — Researchers at the University of São Paulo (USP) in Brazil have characterized a novel family of anti-bacterial toxins present in bacteria, including Salmonella enterica. This species...

New Microfluidic Device Minimizes Loss of High Value Samples

September 9, 2020
Mindzilla

Tempe, AZ — A major collaborative effort that has been developing over the last three years between ASU and European scientists, has resulted in a significant technical advance in X-ray crystallographic...

Genetic Study of Proteins is a Breakthrough in Drug Development for Complex Diseases

September 8, 2020
Mindzilla

Bristol, UK — An innovative genetic study of blood protein levels, led by researchers in the MRC Integrative Epidemiology Unit (MRC-IEU) at the University of Bristol, has demonstrated how genetic data...

New Computational Tool Enables Prediction of Key Functional Sites in Proteins Based on Structure

September 7, 2020
Mindzilla

State College, PA — A new technology that uses a protein’s structure to predict the inner wiring that controls the protein’s function and dynamics is now available for scientists to utilize....

Guilt by Dissociation: Study Sheds Light on Serotonin in Autism

September 2, 2020
Mindzilla

Boca Raton, FL — Recent estimates indicate a prevalence of autism spectrum disorder (ASD) in the United States of 1 in 59 children with a well-established 4:1 male predominance. Individual costs for...

Immune Protein IL-17A Responsible for Lethal Side Effects of Gastric Cancer

August 26, 2020
Mindzilla

Kanazawa, Japan — Gastric cancer, one of the leading causes of cancer-associated mortality worldwide, is renowned for its ability to disseminate throughout the peritoneal cavity. As well as causing...

Sortilin may Hold the Key to Combat Pancreatic Cancer More Effectively

August 24, 2020
Mindzilla

Callaghan, Australia — Pancreatic cancer has an extremely poor prognosis; it is the third most common cause of cancer deaths in the United States. In a novel study published in The American Journal...

Protein Influences Regeneration of Vascular Cells

August 20, 2020
Mindzilla

Bonn, Germany — Through their basic research, physicians at the Heart Center of the University Hospital Bonn have discovered how the communication between individual cells can be influenced with the...

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