1 min readEpilepsy Drugs During Pregnancy Linked with Later Childhood Behavioural Problems

Netherlands — A new study has uncovered an increased risk of behavioural problems in children of mothers with epilepsy who took common antiepileptic drugs during pregnancy.

In the Epilepsia study, behavioural questionnaires were completed for 181 children aged 6 to 7 years, and for most children both parents completed behavioural questionnaires.

Based on parental ratings, valproate- exposed children were most affected, but parents of carbamezepine-, lamotrigine-, and levetiracetam-exposed children also reported behavioural problems.

“It is important to monitor children of mothers with epilepsy and also consider other possible contributing factors, such as family factors. These may provide starting points for interventions to help parents cope with or even decrease child behavioural problems,” said lead author Yfke Huber-Mollema, MsC, of the Stichting Epilepsy Instellingen Nederland (SEIN) and the University of Amsterdam.

Article adapted from a Wiley news release.

Publication: Behavioral problems in children of mothers with epilepsy prenatally exposed to valproate, carbamazepine, lamotrigine, or levetiracetam monotherapy. Yfke Huber‐Mollema et al. Epilepsia (2019): Click here to view.

Antiepileptic drugs, Childhood Behavioural Problems, Epilepsy Drugs, Pregnancy

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