Mindzilla – ACE2

ACE2

Adipose Tissue may be the Source of Inflammatory Factors that Aggravate COVID-19

November 23, 2020
Mindzilla

São Paulo, Brazil — There is growing evidence that adipose tissue plays a key role in the aggravation of COVID-19. One of the theories under investigation is that fat cells (adipocytes) act as a reservoir...

Scientists Identify Synthetic Mini-Antibody to Combat COVID-19

November 5, 2020
Mindzilla

Heidelberg, Germany — The ability of SARS-CoV-2 to infect cells depends on interactions between the viral spike protein and the human cell surface protein ACE2. To enable the virus to hook onto the...

CRISPR Screen Identifies Genes, Drug Targets to Protect Against SARS-CoV-2 Infection

October 27, 2020
Mindzilla

New York, NY — To identify new potential therapeutic targets for SARS-CoV-2, a team of scientists at the New York Genome Center, New York University, and the Icahn School of Medicine at Mount Sinai,...

Researchers Discovered the Second ‘Key’ Used by the SARS-CoV-2 Virus to Enter into Human Cells

October 22, 2020
Mindzilla

Helsinki, Finland — To efficiently infect human cells, SARS-CoV-2, the virus that causes COVID-19, is able to use a receptor called Neuropilin-1, which is very abundant in many human tissues including...

Scientists Uncover the Structural Mechanism of Coronavirus Receptor Binding

September 21, 2020
Mindzilla

London, UK — The spike protein on the surface of the SARS-CoV-2 coronavirus can adopt at least ten distinct structural states, when in contact with the human virus receptor ACE2, according to research...

Scientists Develop Method to Safely Study COVID-19, Other Contagious Diseases

September 21, 2020
Mindzilla

Washington, DC — Scientists and researchers at the U.S. Naval Research Laboratory and National Center for Advancing Translational Sciences (NCATS), submitted their findings to ACS Nano, a monthly peer-reviewed...

COVID-19 Virus Uses Heparan Sulphate to Get Inside Cells

September 17, 2020
Mindzilla

La Jolla, CA — A molecule known as ACE2 sits like a doorknob on the outer surfaces of the cells that line the lungs. Since January 2020, researchers have known that SARS-CoV-2, the novel coronavirus...

Small Proteins Against SARS-CoV-2 Neutralize Infection in Cell Culture

September 10, 2020
Mindzilla

Washington, DC — Using innovative computer-based approaches, researchers have developed protein inhibitors that block the interaction between the SARS-CoV-2 virus and human cell receptor ACE2. In cell...

Researchers Identify Nanobody that may Prevent COVID-19 Infection

September 7, 2020
Mindzilla

Solna, Sweden — Researchers at Karolinska Institutet in Sweden have identified a small neutralizing antibody, a so-called nanobody, that has the capacity to block SARS-CoV-2 from entering human cells....

Study Adds to Evidence That Cells in the Nose are Key Entry Point for SARS CoV-2

August 24, 2020
Mindzilla

Bethesda, MD — Scientists at Johns Hopkins Medicine, experimenting with a small number of human cell samples, report that the “hook” of cells used by SARS-CoV-2 to latch onto and infect...

COVID-19 does not Directly Damage Taste Bud Cells

August 11, 2020
Mindzilla

Athens, GA — A new study from the Regenerative Bioscience Center at the University of Georgia is the first to suggest that COVID-19 does not directly damage taste bud cells. Contrary to previous...

Study Suggests Embryos Could Be Susceptible to Coronavirus

August 5, 2020
Mindzilla

Cambridge, UK — Genes that are thought to play a role in how the SARS-CoV-2 virus infects our cells have been found to be active in embryos as early as during the second week of pregnancy, say scientists...

Researchers Develop New Mouse Model for Sars-Cov-2

August 5, 2020
Mindzilla

New York, NY — Researchers at Yale University School of Medicine have developed a new mouse model to study SARS-CoV-2 infection and disease and to accelerate testing of novel treatments and vaccines...

COVID-19 and the Heart: Searching for Location of SARS-CoV-2 Receptor

July 16, 2020
Mindzilla

Utica, NY — Nearly 20% of all COVID-19-associated deaths are from cardiac complications, yet the mechanisms from which these complications arise have remained a topic of debate in the cardiology community....

Structural Analysis of COVID-19 Spike Protein Provides Insight into Its Evolution

July 13, 2020
Mindzilla

London, UK — Researchers at the Francis Crick Institute have characterised the structure of the SARS-CoV-2 spike protein as well as its most similar relative in a bat coronavirus. The structures provide...

COVID-19: Study Shows Virus can Infect Heart Cells in Lab Dish

July 2, 2020
Mindzilla

Los Angeles, CA — A new study shows that SARS-CoV-2, the virus that causes COVID-19 (coronavirus), can infect heart cells in a lab dish, indicating it may be possible for heart cells in COVID-19 patients...

Cellular Nanosponges Could Soak up SARS-CoV-2

June 17, 2020
Mindzilla

Washington, DC — Scientists are working overtime to find an effective treatment for COVID-19, the illness caused by the new coronavirus, SARS-CoV-2. Many of these efforts target a specific part of...

Three New Studies Identify Neutralizing Antibodies Against SARS-CoV-2

June 16, 2020
Mindzilla

Washington, DC — A trio of papers describes several newly discovered human antibodies that target the SARS-CoV-2 virus, isolated from survivors of SARS-CoV-2 and SARS-CoV infection. Several of these...

COVID-19 Mouse Model will Speed Search for Drugs, Vaccines

June 11, 2020
Mindzilla

St. Louis, MO — The global effort to quickly develop drugs and vaccines for COVID-19 has been hampered by limited numbers of laboratory mice that are susceptible to infection with SARS-CoV-2, the virus...

Researchers Map SARS-CoV-2 Infection in Cells of Nasal Cavity, Bronchia, Lungs

June 2, 2020
Mindzilla

Chapel Hill, NC — In a major scientific study published in the journal Cell, scientists at the UNC School of Medicine and the UNC Gillings School of Global Public Health have characterized the...

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