Mindzilla – ACE2

ACE2

Antibodies that Enhance SARS-CoV-2 Infection — A Possible Factor for Severe COVID-19

May 25, 2021
Mindzilla

Osaka, Japan — A research group from Osaka University led by Professor Hisashi Arase and consisting of researchers from the Research Institute for Microbial Diseases, the Institute for Protein Research,...

Modelling can Predict Mutation “Hotspots” and Antibody Escapers in SARS-CoV-2 Spike Protein

May 21, 2021
Mindzilla

New York, NY — SARS-CoV-2 has evolved to acquire mutations on the spike protein–the part of the virus that protrudes from its surface and latches onto cells to infect them–that enhance...

Novel Coronavirus’ Spike Protein Plays Additional Key Role in Illness

May 4, 2021
Mindzilla

La Jolla, CA — Scientists have known for a while that SARS-CoV-2’s distinctive “spike” proteins help the virus infect its host by latching on to healthy cells. Now, a major new study...

SARS-CoV-2 Curtails Immune Response in the Gut

April 27, 2021
Mindzilla

Cambridge, UK — In an effort to determine the potential for COVID-19 to begin in a person’s gut, and to better understand how human cells respond to SARS-CoV-2, the scientists used human intestinal...

Study details N439K variant of SARS-CoV-2

January 29, 2021
Mindzilla

Glasgow, UK — An international team of researchers has characterized the effect and molecular mechanisms of an amino acid change in the SARS-CoV-2 Spike protein N439K. Viruses with this mutation are...

New Biochemical Clues in Cell Receptors Help Explain How SARS-CoV-2 may Hijack Human Cells

January 22, 2021
Mindzilla

Washington, DC — The SARS-CoV-2 virus may enter and replicate in human cells by exploiting newly-identified sequences within cell receptors, according to work from two teams of scientists. The findings...

Researchers Demonstrate Success with New Therapy for COVID-19

January 20, 2021
Mindzilla

Chicago, IL — A new therapy developed by researchers at Rush University Medical Center is showing success as a way to prevent COVID-19 symptoms in mice. In a study published in the Journal...

SARS-CoV-2 can infect neurons and damage brain tissue, study indicates

January 15, 2021
Mindzilla

New York, NY — Using both mouse and human brain tissue, researchers at Yale School of Medicine have discovered that SARS-CoV-2 can directly infect the central nervous system and have begun to unravel...

Study Shows Endothelial Cell Targeting could Help Fight Covid-19 Symptoms

December 15, 2020
Mindzilla

Stony Brook, NY — For Covid-19 patients with serious lung disease, targeting endothelial cells -cells that comprise the blood vessel wall which regulate oxygen exchange between airways and the bloodstream-...

Scientists Discover How COVID-19 Virus Causes Multiple Organ Failure in Mice

December 8, 2020
Mindzilla

Los Angeles, CA — UCLA researchers are the first to create a version of COVID-19 in mice that shows how the disease damages organs other than the lungs. Using their model, the scientists discovered...

Adipose Tissue may be the Source of Inflammatory Factors that Aggravate COVID-19

November 23, 2020
Mindzilla

São Paulo, Brazil — There is growing evidence that adipose tissue plays a key role in the aggravation of COVID-19. One of the theories under investigation is that fat cells (adipocytes) act as a reservoir...

Scientists Identify Synthetic Mini-Antibody to Combat COVID-19

November 5, 2020
Mindzilla

Heidelberg, Germany — The ability of SARS-CoV-2 to infect cells depends on interactions between the viral spike protein and the human cell surface protein ACE2. To enable the virus to hook onto the...

CRISPR Screen Identifies Genes, Drug Targets to Protect Against SARS-CoV-2 Infection

October 27, 2020
Mindzilla

New York, NY — To identify new potential therapeutic targets for SARS-CoV-2, a team of scientists at the New York Genome Center, New York University, and the Icahn School of Medicine at Mount Sinai,...

Researchers Discovered the Second ‘Key’ Used by the SARS-CoV-2 Virus to Enter into Human Cells

October 22, 2020
Mindzilla

Helsinki, Finland — To efficiently infect human cells, SARS-CoV-2, the virus that causes COVID-19, is able to use a receptor called Neuropilin-1, which is very abundant in many human tissues including...

Scientists Uncover the Structural Mechanism of Coronavirus Receptor Binding

September 21, 2020
Mindzilla

London, UK — The spike protein on the surface of the SARS-CoV-2 coronavirus can adopt at least ten distinct structural states, when in contact with the human virus receptor ACE2, according to research...

Scientists Develop Method to Safely Study COVID-19, Other Contagious Diseases

September 21, 2020
Mindzilla

Washington, DC — Scientists and researchers at the U.S. Naval Research Laboratory and National Center for Advancing Translational Sciences (NCATS), submitted their findings to ACS Nano, a monthly peer-reviewed...

COVID-19 Virus Uses Heparan Sulphate to Get Inside Cells

September 17, 2020
Mindzilla

La Jolla, CA — A molecule known as ACE2 sits like a doorknob on the outer surfaces of the cells that line the lungs. Since January 2020, researchers have known that SARS-CoV-2, the novel coronavirus...

Small Proteins Against SARS-CoV-2 Neutralize Infection in Cell Culture

September 10, 2020
Mindzilla

Washington, DC — Using innovative computer-based approaches, researchers have developed protein inhibitors that block the interaction between the SARS-CoV-2 virus and human cell receptor ACE2. In cell...

Researchers Identify Nanobody that may Prevent COVID-19 Infection

September 7, 2020
Mindzilla

Solna, Sweden — Researchers at Karolinska Institutet in Sweden have identified a small neutralizing antibody, a so-called nanobody, that has the capacity to block SARS-CoV-2 from entering human cells....

Study Adds to Evidence That Cells in the Nose are Key Entry Point for SARS CoV-2

August 24, 2020
Mindzilla

Bethesda, MD — Scientists at Johns Hopkins Medicine, experimenting with a small number of human cell samples, report that the “hook” of cells used by SARS-CoV-2 to latch onto and infect...

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