Mindzilla – Biochemistry

Biochemistry

Synthesis of Potent Antibiotic Follows Unusual Chemical Pathway

January 19, 2021
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State College, PA — Images of a protein involved in creating a potent antibiotic reveal the unusual first steps of the antibiotic’s synthesis. The improved understanding of the chemistry behind...

New Discovery Opens Novel Pathway for High-Titer Production of Drop-In Biofuels

December 18, 2020
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Aarhus, Denmark — New discovery opens novel pathway for high-titer production of drop-in biofuels Using an unusual, light-dependent enzyme and a newly discovered enzymatic mechanism, researchers...

Researchers Solve a 50-Year-Old Enzyme Mystery

July 13, 2020
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St Lucia, Australia — Advanced herbicides and treatments for infection may result from the unravelling of a 50-year-old mystery by University of Queensland researchers. The research team, led by...

Towards Improved Wound Healing — Chemical Synthesis of a Trefoil Factor Peptide

July 9, 2020
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Vienna, Austria — The three known human trefoil factor family peptides TFF1, TFF2 and TFF3 are mainly produced by the gastrointestinal mucosa. Named after their trefoil-like folded structure, the molecules...

Enzymes as Double Agents: New Mechanism Discovered in Protein Modification

July 9, 2020
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Münster, Germany — Proteins are the workers in a cell and, as the “basic element of life”, are responsible for the most widely varying metabolic processes. In plants, for example, they...

Moving Faster in a Crowd

September 2, 2019
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State College, PA — Cell particles move more quickly through a crowded cellular environment when the crowding molecules are non-uniformly distributed. New research also shows that particle transport...

Body Temperature Regulation: How Fever Comes

September 5, 2018
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Kanazawa, Japan — The appearance of fever is associated with the release in the hypothalamus of a lipid compound called prostaglandin E2 (PGE2), which has an important role in the regulation of body...

Research Reveals Mechanism of Biological Noise Cancellation

September 5, 2018
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Kanazawa, Japan — Noise is usually considered a nuisance, for example when preventing us from clearly hearing what someone is saying. The general concept of noise applies more broadly.

Gestational Diabetes May Predispose to Postpartum Depression Symptoms, Says Study

September 5, 2018
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Kuopio, Finland — Mothers diagnosed with gestational diabetes mellitus (GDM) have an elevated risk of developing postpartum depression symptoms, according to a new Finnish study.

Scientists Identify Hormone Link Between Diabetes and Hypertension

September 5, 2018
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Columbus, OH — Physician researchers with The Ohio State University College of Medicine at the Wexner Medical Center say increased levels of the hormone aldosterone, already associated with hypertension,...

Inhibiting NF-κB Improves Heart Function in a Mouse Model of Duchenne Muscular Dystrophy

August 31, 2018
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Charleston, SC — Duchenne muscular dystrophy (DMD) is a devastating genetic disease that impairs cardiac and skeletal muscle development. People with DMD gradually lose ambulation in childhood, acquire...

Regulatory and Effector B Cells Control Scleroderma

August 30, 2018
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Kanazawa, Japan — Systemic sclerosis (SSc, also known as scleroderma), a connective tissue disorder of autoimmune etiology, is characterized by excessive fibrosis in the skin and various internal o...

Mapping Out Cancer’s Movements

August 29, 2018
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Washington, DC — Cancer researchers struggle to identify tumour cells that are interspersed within nonmalignant tissues because tumour cells exploit the tissue environment and monopolize available resources...

HIV/AIDS Research Yields Dividends Across Medical Fields

August 28, 2018
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Bethesda, Maryland — Since the first cases of AIDS were reported in the United States 37 years ago, the National Institutes of Health has invested more than $69 billion in the understanding, treatment...

Research Reveals Potential Biomarkers of Cerebral Aneurysm Risk

August 25, 2018
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United Arab Emirates – Expansive arterial remodelling (EAR) comprises a genetically programmed biological response designed to restore homeostatic levels of arterial wall stress after an increase...

Disrupted Nitrogen Metabolism might Spell Cancer, Suggests Study

August 13, 2018
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Rehovot, Israel — Researchers at the Weizmann Institute of Science, in collaboration with colleagues from the National Cancer Institute and elsewhere, have now shown that in many cancers, the patient’s...

Wearable Yeast ‘Microbrewery’ Helps Save Human Body from Radiation Damage, Says Study

August 11, 2018
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West Lafayette, IN — The same way that yeast yields beer and bread can help hospital lab workers better track their daily radiation exposure, enabling a faster assessment of tissue damage that could...

Research Discovers Mechanism of Fibrosis Development

August 10, 2018
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Munich, Germany — Idiopathic pulmonary fibrosis (IPF) is an incurable lung disease of unknown origin with limited treatment options. Research suggests that the signalling molecule WNT5A plays a key...

Striking a Balance Between Immunity and Inflammation

August 7, 2018
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Riverside, CA — Hookworms infect nearly 430 million people in the world, mostly in countries where sanitation is poor, and people often walk barefoot. The body’s immune system is critical to attacking...

Assembly of Fluctuating Molecules in Artificial Cell Membrane

August 4, 2018
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Toyohashi, Japan — Lipids and membrane proteins existing in cell membranes, which locates at the outermost layer of cells, are responsible for recognizing extracellular environments and transferring...

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