Mindzilla – CRISPR-Cas9

CRISPR-Cas9

Receptors for Immune Defence

March 17, 2020
Mindzilla

Munich, Germany — Adaptive immunity is a powerful defense mechanism in vertebrates. A finely tuned interplay of different cell types provides a pathogen-specific immune response to eliminate for example...

Strong Signals Show How Proteins Come and Go

March 10, 2020
Mindzilla

Houston, TX — A novel system to amplify gene expression signals could be a game-changer for scientists who study the regulatory processes in cells that are central to all life. The Rice University...

Huge Bacteria-Eating Viruses Close Gap Between Life and Non-Life

February 13, 2020
Mindzilla

Berkeley, CA — Scientists have discovered hundreds of unusually large, bacteria-killing viruses with capabilities normally associated with living organisms, blurring the line between living microbes...

New Tumour-Driving Mutations Discovered in Under-Explored Regions of Cancer Genome

January 20, 2020
Mindzilla

Toronto, ON — In an unprecedented pan-cancer analysis of whole genomes, researchers at the Ontario Institute for Cancer Research (OICR) have discovered new regions of non-coding DNA that, when altered,...

Disruption of Glycine Receptors to Study Embryonic Development and Brain Function

December 19, 2019
Mindzilla

Jupiter, FL — Glycine receptors are one of the most widely distributed inhibitory receptors in the central nervous system and have important roles in a variety of physiological processes. Researchers...

Researchers Unlock Potential to Use CRISPR to Alter Microbiome

October 7, 2019
Mindzilla

London, ON — Researchers at Western University have developed a new way to deliver the DNA-editing tool CRISPR-Cas9 into microorganisms in the lab, providing a way to efficiently launch a targeted...

New Crispr Class Expands Genetic Engineering Toolbox

September 25, 2019
Mindzilla

Durham, NC — Biomedical engineers at Duke University have used a previously unexplored CRISPR technology to accurately regulate and edit genomes in human cells. With this new approach, the researchers...

Novel Nanoparticles Deliver CRISPR Gene Editing Tools into Cell with Much Higher Efficiency

July 15, 2019
Mindzilla

Medford/Somerville, MA — A research collaboration between Tufts University and the Chinese Academy of Sciences has led to the development of a significantly improved delivery mechanism for the CRISPR/Cas9...

Linking Phenotypes to Genotypes: Newly Devised Gene-Editing Strategy

July 9, 2019
Mindzilla

The power and convenience of modern-day word-processing programs, like Microsoft Word, have revolutionized our daily tasks. Need to create a quick resume for a new job opportunity? Procrastinating...

Researchers Find Cause of Rare, Fatal Disease That Turns Babies’ Lips and Skin Blue

June 19, 2019
Mindzilla

Cincinnati, OH — Scientists used a gene editing method called CRISPR/Cas9 to generate mice that faithfully mimic a fatal respiratory disorder in newborn infants that turns their lips and skin blue....

New Genetic Weapons Challenge Sickle Cell Disease

June 3, 2019
Mindzilla

Houston, TX — Help for patients with sickle cell disease may soon come from gene editing to fix the mutation that causes the disease and boost the patient’s own protective fetal haemoglobin. New...

Risk and Unnaturalness Cannot Justify EU’s Strict Policy on GMO, Research Concludes

April 24, 2019
Mindzilla

Copenhagen, Denmark — The EU’s policy on GMO is extremely strict and prevents new GMO crops from being authorized. The policy is based on arguments about the risk and unnaturalness of GMO plants...

Researchers Optimize Gene Editing for SCD and Beta Thalassemia

March 29, 2019
Mindzilla

Boston, MA — Researchers at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center and the University of Massachusetts Medical School have developed a strategy to treat two of the most...

New Method to Boost CRISPR Efficiency Developed

March 6, 2019
Mindzilla

Dallas, TX — Scientists have developed a method to boost the efficiency of CRISPR gene editing in Duchenne muscular dystrophy (DMD), according to a study that could have implications for optimizing...

Scientists Sharpen Their Molecular Scissors and Expand Gene Editing Toolbox

February 25, 2019
Mindzilla

Winston-Salem, NC — Wake Forest Institute for Regenerative Medicine (WFIRM) scientists have figured out a better way to deliver a DNA editing tool to shorten the presence of the editor proteins in...

CRISPR Gene Editing Makes Stem Cells ‘Invisible’ to Immune System

February 18, 2019
Mindzilla

San Francisco, CA — UC San Francisco scientists have used the CRISPR-Cas9 gene-editing system to create the first pluripotent stem cells that are functionally “invisible” to the immune...

Folliculin Mutations Disrupt Embryo Implantation

February 7, 2019
Mindzilla

Seattle, WA — New information is unfolding on the genetic controls of an early turning point in pregnancy. As the tiny, dividing cell mass, the blastocyst, travels from the oviduct and lodges in the...

Process Makes Stem-Cell-Derived Heart Cells Light Up

December 20, 2018
Mindzilla

State College, PA — A faster, more cost-efficient, and more accurate method of examining the effectiveness of human pluripotent stem-cell-derived cardiac muscle cells has been discovered, according...

Stem Cell Researchers Develop Promising Technique to Generate New Muscle Cells in Lab

December 13, 2018
Mindzilla

Houston, TX — To help patients with muscle disorders, scientists at The University of Texas Health Science Center at Houston (UTHealth) have engineered a new stem cell line to study the conversion...

Moths and Magnets could Save Lives

November 13, 2018
Mindzilla

Houston, TX — A new technology that relies on a moth-infecting virus and nanomagnets could be used to edit defective genes that give rise to diseases like sickle cell, muscular dystrophy and cystic...

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