Mindzilla – Epigenomics

Epigenomics

Key Role Found for Enzymes in DNA Replication and Sensitivity to Chemotherapeutic Drugs

August 9, 2018
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Barcelona, Spain — During cell growth, cells copy their DNA through a process called DNA replication. For this process to be accurate, the genetic and epigenetic information must be copied flawless...

Epigenetic Markers of Ovarian Cancer

August 7, 2018
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Baltimore, MD — Researchers identify that silencing of the GULP1 gene expression by methylation plays an important role in ovarian carcinogenesis.

Study Explains Epigenetic Mechanisms Behind Autoimmune Diseases

August 4, 2018
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São Paulo, Brazil — A group of researchers at the University of São Paulo (USP) in Brazil used a DNA editing tool called CRISPR/Cas9 to manipulate on of the genes associated to the autoaggressive T...

DNA Methylation Related to Liver Disease Among Obese Patients, Study Shows

July 19, 2018
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Phoenix, AZ — DNA methylation is a molecular process that helps enable our bodies to repair themselves, fight infection, get rid of environmental toxins, and even to think. But sometimes this process...

Microgravity Conditions Affect DNA Methylation of Muscle Cells, Study Finds

May 23, 2018
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Japan — Astronauts go through many physiological changes during their time in spaceflight, including lower muscle mass and slower muscle development. Similar symptoms can occur in the muscles of people...

Scientists Identify Cause of Resistance to Breakthrough Breast and Ovarian Cancer Drug

May 10, 2018
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London, UK — Scientists have identified a mutation that gives cancer cells resistance to the breakthrough cancer treatment olaparib and other PARP inhibitors.

Researcher Discovers Mechanisms and Epigenetic Markers with Implications for Diseases Ranging from Cancers to Infertility

May 2, 2018
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College Park, MD — A UMD researcher has uncovered new mechanisms that dictate the development of germline stem cells or germ cells, the only cell type capable of passing genetic information on to the...

An Epigenetic Key to Unlock Behaviour Change

October 17, 2017
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Toronto, ON, Canada — When it comes to behaviour, researchers have moved beyond the “nature versus nurture” debate. It’s understood that genes and environment both play a role. However,...

New Approach Developed to Model Human Immune Diversity in Lab

July 26, 2017
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La Jolla, CA – In their latest study, researchers at La Jolla Institute for Allergy and Immunology, developed a new approach to model human immune variation in the lab that overcomes...

Team Unveils Complete Epigenomes of the Most Frequent Tumours

June 8, 2017
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Barcelona, Spain — A research team from the Bellvitge Biomedical Research Institute (IDIBELL) has managed to characterize the complete epigenomes of the most frequent tumours, including those...

Mouse’s Internal Clock Could Reveal the Secrets of Ageing, Says Study

April 25, 2017
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Hinxton, UK — Recent research has shown that changes to our DNA are a good indicator of our biological age. These changes – known as DNA methylation – are modifications to the outer...

After Genetics, and Epigenetics, the Epitranscriptome Might Offer New Answers to Some Diseases

March 22, 2017
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Barcelona, Spain — Our genome is made up of 6,000 million pieces of DNA that combine four “flavours”: A, C, G and T (Adenine, Cytosine, Guanine and Thymine). It is our Alphabet. But...

Cultural Differences May Be Reflected in DNA, Study Shows

January 10, 2017
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San Fransisco, CA – A UC San Francisco-led study has identified signatures of ethnicity in the genome that appear to reflect an ethnic group’s shared culture and environment, rather than...

Epigenetic Research Gives Insights to How Human Embryos Develop

December 15, 2016
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Cambridge, UK — Researchers have discovered new insights into how one of the two X-chromosomes is silenced during the development of female human embryos and also in lab-grown stem cells. X-chromosome...

Scientists Find Colorectal Tumours Present Epigenetic Heterogeneity that Relates to the Clinical Course of the Disease

August 19, 2016
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Barcelona, Spain — A new study led by Dr. Manel Esteller, Director of the Epigenetics and Cancer Biology Program (PEBC) of Bellvitge Biomedical Research Institute (IDIBELL), ICREA researcher and...

Not Only Trauma But Also the Reversal of Trauma is Inherited, Says Study

June 23, 2016
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Zürich, Switzerland — Traumatic experiences in childhood increase the risk of developing behavioural and psychiatric disorders later in life. It is also known that the consequences of a trauma...

Epigenetic Modification Increases Susceptibility to Obesity and Predicts Fatty Liver, Research Suggests

May 24, 2016
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Düsseldorf, Germany — Scientists of the German Center for Diabetes Research (DZD) led by the German Institute of Human Nutrition (DIfE) have shown in a mouse model that the epigenetic modification of...

Research Finds Cancer Can Arise from Changes in the Proteins that Package DNA

May 13, 2016
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New York, NY — A mutation that affects the proteins that package DNA–without changing the DNA itself–can cause a rare form of cancer, according to new findings in this week’s Science...

Key Gene in Development of Gluten Intolerance Found in ‘Junk’ DNA

April 8, 2016
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Basque, Spain — Coeliac disease is a chronic, immunological disease that is manifested as intolerance to gluten proteins present in wheat, rye and barley.

New Epigenetic Technique Could Identify Plant, Animal DNA Switches Much Faster and Cheaper

February 10, 2016
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Wageningen, NL — Epigenetics is a fast-growing field of research all over the world. Ecological epigenetics has now been further advanced thanks to the development of a new research technique.

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