New Insights into How Gene Activity Drives Development of Cartilage
Whittier, CA — Anyone with arthritis can appreciate how useful it would be if scientists could grow cartilage in the lab.
Functional Genomics
Twenty-Five Genetic Changes That Could Have Extended Human Lifespan Identified
Barcelona, Spain — Senescence, or biological ageing, refers to the general deterioration of an organism’s physiological functions, leading to increased susceptibility to diseases and ultimately...
Research Study Sheds New Light on Relationship Between Genes and Bone Fracture Risk
Boston, MA — Researcher reports findings from a large international collaboration that identified 15 variations in the genome that are related to the risk of suffering bone fractures, which are a major...
Study Reveals Mutations in Molecule That May Have Helped Mammoths Tolerate Cold
New York, NY – Columbia University biomedical researchers have captured close-up views of TRPV3, a skin-cell ion channel that plays important roles in sensing temperature, itch, and pain.
Researchers Identify New Genes that may Contribute to Alzheimer’s Disease
Boston, MA — Researchers from Boston University School of Medicine, working with scientists across the nation on the Alzheimer’s Disease Sequencing Project (ADSP), have discovered new genes that...
Koala Virus Could Explain Why Humans Have ‘Junk’ DNA, Says Study
St Lucia, QLD, Australia — A koala virus could help researchers explain millions of years of accumulated ‘junk’ DNA in the human genome.
Big-Data Study Pinpoints More Than 150 Genes Associated with Atrial Fibrillation
Ann Arbor, MI — Drawing on genomic data from more than one million individuals, researchers from the University of Michigan have led a large collaborative effort to discover as-yet unknown genetic...
Molecular Mechanisms of Rare Skin Disease Uncovered
New York, NY — Keratinocyte skin cells are common targets of the beta subtype of human papilloma virus. This usually harmless infection causes skin disease in people with rare gene mutations.
Researchers Reveal Hidden Rules of Genetics for How Life on Earth Began
Chapel Hill, NC — All living things use the genetic code to “translate” DNA-based genetic information into proteins, which are the main working molecules in cells.
Research Identifies Susceptible Genes for Childhood Chronic Kidney Disease
Kobe, Japan — Childhood nephrotic syndrome is the most frequently occurring chronic kidney disease among children. A Japanese research team has identified a group of genes that are strongly related...
Switching Sides: Betrayal of an Anti-Cancer Gene
Rehovot, Israel — It doesn’t often happen that army generals switch sides in the middle of a war, but when cancer’s attack is underway, it may even cause a gene that acts as the body’s...
Blindness Gene Discovered
Geneva, Switzerland — Researchers have identified the gene responsible for a recessive genetic disorder that causes degeneration of the eye and blindness.
Ageing-Associated Skin Wrinkles and Hair Loss Reversed in Mouse Model
Birmingham, AL — Wrinkled skin and hair loss are hallmarks of ageing. What if they could be reversed?
Identified RNA Molecules that Regulate Action of Male Hormone in Prostate Cancer
São Paulo, SP, Brazil — A study detected in tumoural tissue hundreds of RNAs that do not encode proteins but appear to regulate effects of androgens and androgen receptors on gene expression in tum...
Single Genetic Change in Gut Bacteria Alters Host Metabolism
Boston, MA — Scientists have found that deleting a single gene in a particular strain of gut bacteria causes changes in metabolism and reduced weight gain in mice, according to a study in the journ...
Cross Species Transfer of Genes has Driven Evolution
Adelaide, Australia — Far from just being the product of our parents, University of Adelaide scientists have shown that widespread transfer of genes between species has radically changed the genomes...
How Satellite RNA Leads to Cancer
La Jolla, CA — Only some of us have satellite TV in our homes, but all of us have satellite DNA in cells in our bodies. Working copies of satellite DNA (called satellite RNAs) are high in certain types...
Computational Models Provide Novel Genetic Insights into Atherosclerosis
Frankfurt, Germany — Researchers have identified a new gene-activation pathway caused by lipids associated with coronary artery disease, a finding that could help identify new directions in research...
Scientists Discover How Antiviral Gene Works
Bronx, NY — Now, researchers at Albert Einstein College of Medicine, part of Montefiore, have discovered the secret to the gene’s success: The enzyme it codes for generates a compound that stops...
Encrypted Messages in Biological Processes
Aarhus C, Denmark — RNA modifications can encrypt the RNA code and are responsible for a very sophisticated control of RNA function. A Danish-German research team has shown that modified RNA bases have...
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