Mindzilla – Gene Technology

Gene Technology

Novel Technology Provides New Tools for Controlling Genetic Inheritance, Genome Engineering

February 7, 2018
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La Jolla, CA — In 2015, University of California San Diego biologists Ethan Bier and Valentino Gantz developed a technology known as “active genetics,” which results in parents transmitting...

Systematic Study Reveals Multiple New and Unusual Bacterial Immune Defence Mechanisms

January 25, 2018
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Rehovot, Israel — Until a decade ago, scientists were not aware that bacteria had complex immune systems – ones that could keep up with the pace of evolution in viruses called phages that infect...

Searching for the CRISPR Swiss Army knife

December 12, 2017
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Madrid, Spain — Scientists at the University of Copenhagen, led by the Spanish Professor Guillermo Montoya, are investigating the molecular features of different molecular scissors of the CRISPR-Cas...

‘CRISPR-Gold’ Fixes Duchenne Muscular Dystrophy Mutation in Mice

October 4, 2017
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Berkeley, CA — Scientists at the University of California, Berkeley, have engineered a new way to deliver CRISPR-Cas9 gene-editing technology inside cells and have demonstrated in mice that the technology...

Conformational Changes Within Protein Domains Suggest Mutations to Make Hyper-Accurate Cas9s

September 21, 2017
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Berkeley, CA — Scientists at the University of California, Berkeley and Massachusetts General Hospital have identified a key region within the Cas9 protein that governs how accurately CRISPR-Cas9...

Early Gene-Editing Success Holds Promise for Preventing Inherited Diseases

August 2, 2017
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La Jolla, CA — Scientists have corrected a disease-causing mutation in early stage human embryos with gene editing. The technique, which uses the CRISPR-Cas9 system, corrected the mutation for...

Novel Technique Enables Safer Gene-Editing Therapy Using CRISPR, Says Study

June 30, 2017
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Austin, TX — Scientists from The University of Texas at Austin took an important step toward safer gene-editing cures for life-threatening disorders, from cancer to HIV to Huntington’s disease,...

Study Reveals Key Steps in CRISPR-Cas3 Function at Near-Atomic Resolution

June 29, 2017
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Boston, MA — Harvard Medical School and Cornell University scientists have generated near-atomic resolution snapshots of CRISPR that reveal key steps in its mechanism of action.

Firefly Gene Illuminates Ability of Optimized CRISPR-Cpf1 to Efficiently Edit Human Genome

June 23, 2017
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Jupiter, FL – Scientists on the Florida campus of The Scripps Research Institute (TSRI) have improved a gene-editing technology to advance the system’s ability to target, cut and paste...

New Device to Overcome Pig Genome Flaw Developed

May 25, 2017
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Kent, UK — Scientists at the University of Kent, working with colleagues from the genetics research industry, have developed a new genetic screening device and protocol that helps pig breeding.

Scientists Create Innovative Technique for Studying How Chlamydia Invades Our Immune System

April 28, 2017
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Hinxton, UK — Scientists at the Wellcome Trust Sanger Institute and their collaborators at the University of British Columbia have created an innovative technique for studying how chlamydia interacts...

Gene-Editing Tool Rescues Photoreceptors in Mice from a Variety of Mutations

March 14, 2017
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Bethesda, MD — Silencing a gene called Nrl in mice prevents the loss of cells from degenerative diseases of the retina, according to a new study.

New Tool for Quick and Easy DNA Deletion in Living Cells Developed

March 6, 2017
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Barcelona, Spain — Genomics is the field of research studying how our “genome”, or entire DNA sequence, specifies a human being, and how errors in this sequence give rise to disea...

Tool to Identify Interactions Between RNA and DNA Molecules Developed

March 1, 2017
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La Jolla, CA — Bioengineers at the University of California San Diego have developed a new tool to identify interactions between RNA and DNA molecules.

CRISPR Meets Single-Cell Sequencing in New Screening Method

January 24, 2017
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Vienna, Austria — Genome editing using CRISPR/Cas9 “gene scissors” is a powerful tool for biological discovery and for identifying novel drug targets. In pooled CRISPR screens,...

Researchers Use Supercomputers to Create All-Atom Simulation of Genome Editing in Action

January 12, 2017
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Austin, TX — One of the most talked about biological breakthroughs in the past decade was the discovery of the genome editing tool CRISPR/Cas9, which can alter DNA and potentially remove the root...

Enhanced CRISPR Allows Scientists to Explore All Steps of Health and Disease in Every Cell Type

November 29, 2016
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Hinxton, UK — Wellcome Trust Sanger Institute and University of Cambridge researchers have created sOPTiKO, a more efficient and controllable CRISPR genome editing platform.

GUIDE-Seq: Genetic Duct Tape and DNA Damage

September 30, 2016
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Houghton, MI — Double-stranded breaks in DNA can be detected with several technologies. Doing so in plants is exceptionally difficult, but GUIDE-Seq shows promise in new studies.

Scientists Develop DNA-Altering Technology to Tackle Diseases

September 13, 2016
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Singapore — Researchers in Singapore have developed a new protein that can alter DNA in living cells with much higher precision than current methods.

Modifying a Living Genome with Genetic Equivalent of ‘Search and Replace’

August 19, 2016
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Washington, DC — Researchers including George Church have made further progress on the path to fully rewriting the genome of living bacteria.

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