Mindzilla – Neurodegeneration

Neurodegeneration

Protein from the Liver may Cause Alzheimer’s Disease in the Brain

September 15, 2021
Mindzilla

Bentley, Australia — Amyloid protein made in the liver can cause neurodegeneration in the brain, according to a new study in the open-access journal PLOS Biology, by John Mamo of Curtin University...

Biologists Identify Bacterial Proteins that Promote Neurodegeneration, Opening a New Therapeutic Approach for Neurodegenerative Diseases

September 9, 2021
Mindzilla

Hong Kong, China — Growing evidence indicates that gut microbiota plays a critical role in regulating the progression of neurodegenerative diseases such as Parkinson’s disease (PD) and Alzheimer’s...

New Signalling Pathway could Shed Light on Damage Repair During Brain Injury

July 8, 2021
Mindzilla

Plymouth, UK — Most human cells are able to repair damage by dividing at wounds. But mature nerve cells (neurons) in our brain are different. If they attempt division, they will likely die –...

Researchers Identify Protein Oroduced after Stroke that Triggers Neurodegeneration

April 28, 2021
Mindzilla

Dallas, TX — Researchers with the Peter O’Donnell Jr. Brain Institute at UT Southwestern have identified a new protein implicated in cell death that provides a potential therapeutic target that...

Reversal of Glial Scar Tissue Back to Neuronal Tissue Through Neuroregenerative Gene Therapy

November 17, 2020
Mindzilla

Guangdong, China — Brain or spinal cord injury often results in glial scar tissue that is correlated to neural functional loss. Glial scar is a well-known obstacle for neural regeneration due to its...

When Astrocytes Attack: Stem Cell Model Shows Possible Mechanism Behind Neurodegeneration

June 2, 2020
Mindzilla

New York, NY — A new study published today in Neuron led by The New York Stem Cell Foundation (NYSCF) Research Institute’s Dr. Valentina Fossati, creates astrocytes – an integral support...

Treatment to Reset Immune Cells Markedly Improves TBI Symptoms

February 26, 2020
Mindzilla

Baltimore, MD — Researchers at the University of Maryland School of Medicine (UMSOM) found that targeting overactive immune cells in the brain with an experimental drug could limit brain cell loss...

Researchers Discover How Cellular Senescence Leads to Neurodegeneration

January 30, 2020
Mindzilla

Novato, CA — Although a link has been established between chronic inflammation and neurodegenerative diseases, there have been many open questions regarding how cellular senescence, a process whereby...

Objective Subtle Cognitive Difficulties Predict Amyloid Accumulation and Neurodegeneration

January 3, 2020
Mindzilla

La Jolla, CA — Researchers at University of California San Diego School of Medicine and Veterans Affairs San Diego Healthcare System report that accumulating amyloid — an abnormal protein linked...

Tau-Mediated RNA Splicing Errors Linked to Alzheimer’s Disease

October 8, 2019
Mindzilla

Houston, TX — A collaborative study published today in the journal Cell Reports provides evidence for a new molecular cause for neurodegeneration in Alzheimer’s disease. The study, led by researchers...

Multiple Sclerosis: Endogenous Retrovirus HERV-W Key to Nerve Tissue Damage

June 27, 2019
Mindzilla

Early disease stages of MS are primarily characterised by immune cell infiltration of the CNS. This causes inflammation that damages the so-called myelin sheaths. Myelin sheaths are electrically insulating...

Researchers Develop Breakthrough Process to Create Cancer-Killing Drugs

June 4, 2019
Mindzilla

Hanover, NH — A research team at Dartmouth College has developed a new strategy for drug discovery and development that can be used to produce targeted therapies against diseases such as cancer and...

Neurons with Good Housekeeping are Protected from Alzheimer’s

December 17, 2018
Mindzilla

New York, NY — Some neurons in the brain protect themselves from Alzheimer’s with a cellular cleaning system that sweeps away toxic proteins associated with the disease, according to a new study...

Researchers Find Infectious Prions Throughout Eyes of Patients with Deadly Sporadic Creutzfeldt-Jakob Disease

November 20, 2018
Mindzilla

La Jolla, CA — By the time symptoms of sporadic Creutzfeldt-Jakob disease (sCJD) are typically discovered, death is looming and inevitable. But, in a new study, researchers at University of California...

Collaboration Yields Possible Treatment for Rare Neurodegenerative Disorder

October 23, 2018
Mindzilla

Memphis, TN — St. Jude Children’s Research Hospital investigators have developed a new class of compounds that extended the lives and eased symptoms of mice with a progressive neurodegenerative...

Role of Atg2 Protein in Tethering Pre-Autophagosomal Membranes to Endoplasmic Reticulum

October 23, 2018
Mindzilla

Tokyo, Japan — Researchers at Tokyo Institute of Technology have analyzed the Atg protein Atg2, whose function had been completely unknown, and have discovered that Atg2 tethers the pre-autophagosomal...

New Immunotherapy Targeting Blood-Clotting Protein

October 16, 2018
Mindzilla

San Francisco, CA — Normally, the blood protein fibrin does not enter the brain. But in several neurological disorders, the blood-brain barrier–which keeps large molecules in the blood from entering...

Alzheimer’s-Associated Tau Protein Disrupts Molecular Transport within Neurons

September 6, 2018
Mindzilla

Boston, MA — A multi-institutional study led by investigators at Massachusetts General Hospital (MGH) and Johns Hopkins School of Medicine has found how the abnormal form of tau that accumulates in...

New Strategy Shows Promise for Earlier Detection of Alzheimer’s Disease

September 5, 2018
Mindzilla

Miami, FL — Finding an effective way to identify people with mild cognitive impairment who are most likely to go on to develop Alzheimer’s disease has eluded researchers for years.

Vicious Circle Leads to Loss of Brain Cells in Old Age

September 3, 2018
Mindzilla

Bonn, Germany — The so-called CB1 receptor is responsible for the intoxicating effect of cannabis. However, it appears to act also as a kind of “sensor” with which neurons measure and control...

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