Mindzilla – Oncogenomics

Oncogenomics

Weak Point in Deadly Eye Melanoma Identified

September 7, 2018
Mindzilla

St. Louis, MO — A natural plant compound exploits a newly identified Achilles’ heel in a cancer of the eye, uveal melanoma. In human cancer cells growing in the lab, the compound shuts down the...

Scanning Thousands of Molecules Against an Elusive Cancer Target

September 7, 2018
Mindzilla

Rockville, MD — Researchers at the National Center for Advancing Translational Sciences (NCATS), part of the National Institutes of Health, have developed a system to accelerate the discovery of chemical...

‘Chromosomal Catastrophes’ in Colorectal Cancer

September 6, 2018
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London, UK — ‘Chromosomal catastrophes’ have been found to occur along the evolutionary timeline of colorectal cancer development, according to new research led by Queen Mary University...

Research Suggests A Master Switch Controls Aggressive Breast Cancer

September 5, 2018
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La Jolla, CA — A team at the Salk Institute has identified a master switch that appears to control the dynamic behaviour of tumour cells that makes some aggressive cancers so difficult to treat. The...

Mutations, Drugs Drive Cancer by Blurring Growth Signals

September 3, 2018
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San Francisco, CA ― Genetic mutations in a form of non-small cell lung cancer (NSCLC) may drive tumour formation by blurring cells’ perception of key growth signals, according to a new laboratory...

Scientists Unlocking Secrets of Cell Division in Cancer

August 30, 2018

Charleston, SC — Scientists at Hollings Cancer Center at the Medical University of South Carolina have found that some cells can divide without a molecule that was previously thought necessary.

Protein Modifications Pointing to Cancer

August 29, 2018
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Zürich, Switzerland — Cells use different signals to react to stress and to inform other body cells. Triggers are, for example, cancer or inflammatory diseases.

Researchers Reveal Cause of Aggressive Skin Cancer in Patients with Butterfly Syndrome

August 27, 2018
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Philadelphia, PA — Patients with a rare skin disease, commonly called Butterfly Syndrome, that causes chronic blistering and extensive scarring also develop an aggressive and fatal form of cancer early...

Scientists Close In on Mystery Surrounding Dangerous Blood Syndromes

August 23, 2018
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Cincinnati, OH — Scientists may be on the road to solving the mystery of a group of mostly incurable blood diseases called myelodysplastic syndromes (MDS), which cause people to have immature, malfunctioning...

Researchers Find Pathways that Uncover Insight into Development of Lung Cancer

August 20, 2018
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Lebanon, NH — A study conducted at Dartmouth turns up two significant pathogenic pathways that provide new understanding of the mechanisms by which a chromosome, previously identified as a lead susceptibility...

Improved Statistical Methods to Understand Gene Interactions in Cancer Development

August 15, 2018
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New Orleans, LA – Research led by Dr. Hui-Yi LinAssociate Professor of Biostatistics at LSU Health New Orleans School of Public Health, has developed another novel statistical method for evaluating...

Genetic Mutations of Appendix Cancer Identified, may Impact Treatment

August 9, 2018
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La Jolla, CA — Appendix cancer is currently treated like colon cancer, but significant differences may alter therapy choices.

Research Discovers Hidden Signs in Cancer Tissue

August 8, 2018
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Zürich, Switzerland — A research team led by Gunnar Raetsch, Professor of Biomedical Informatics at ETH Zurich, has evaluated the largest set of genetic data in cancer medicine: The Cancer Genome Atlas...

Discovery of New Tumour Suppressor Previously Thought to be Oncogene

August 7, 2018
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Madrid, Spain — A gene that has for decades been considered a tumour promoter, the PLK1 gene, can also perform the exact opposite function: halting the development of cancer.

New Strategy for Cancer Therapy Spells Double Trouble for Tumours

August 4, 2018
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La Jolla, CA — Scientists at Scripps Research have uncovered a new strategy to kill tumours, including some triple-negative breast cancers, without harming healthy cells, a discovery that could lead...

Scientists Identify New Mechanisms Underlying Paediatric Kidney Cancer

August 2, 2018
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Dallas, TX — Connecting two previously unrelated insights about the formation of pediatric kidney cancer, researchers at UT Southwestern Medical Center have uncovered the means by which the cancer continues...

Research Suggests New Approach to Targeted Cancer Therapy

August 1, 2018
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Moscow, Russia — During carcinogenesis malignant cells undergo uncontrolled division, causing the tumour dissemination. Target therapy is an actively developing area of cancer treatment.

Reliable, Easy-to-Use Mouse Model for Investigating Bone Metastasis

July 31, 2018
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Tokyo, Japan — Researchers at Tokyo Institute of Technology propose an improved mouse model that could revolutionize bone metastasis research. Their method, which involves injecting cancer cells via...

Breast Cancer Fuelled by Mysterious Yin Yang Protein

July 24, 2018
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London, UK — Scientists have unveiled clues about a mysterious molecule called Yin Yang1 – and revealed it may fuel tumour growth in breast cancer.

Obesity and Inflammation — A Deadly Combination for Prostate Cancer, Says Study

July 18, 2018
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Osaka, Japan — Inflammation and evasion of the immune system have been reported to be some of the new hallmarks of cancer. Notably, a high-fat diet (HFD) causes obesity and chronic inflammation, and...

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