Researchers Clarify Role of Mutations in Glioblastoma
Chapel Hill, NC — Researchers have discovered how different mutations in a specific gene help drive glioblastoma, the most lethal form of brain cancer.
Oncogenomics
Breast Cancer Growth Signals are Enhanced By Protein Outside Cells
Argentina — New research uncovers how a sticky protein called fibronectin promotes the activity of estrogen in breast cancer cells.
Loss of Cilia Leads to Melanoma
Zürich, Switzerland — Researchers at the University of Zurich have now shown that cilia, the fine sensory antennae, play a key role in the formation of melanoma.
A New Tactic for Starving Tumours
New York, NY — A tumour’s goal is simple: to grow, grow, grow, by making more cancer cells. But that often means growing so fast that the oxygen supply gets scarce, at which point cells within...
New Study Confirms Higher Cancer Rate in Women with Dense Breast Tissue
Oak Brook, IL — Researchers using automated breast density measurements have found that women with mammographically dense breast tissue have higher recall and biopsy rates and increased odds of screen-detected...
Genomics Offers New Treatment Options for Infants with Range of Soft Tissue Tumours
Würzburg, Germany — The genetic causes of a group of related infant cancers have been discovered by scientists at the Wellcome Sanger Institute, the University of Wuerzburg and their collaborators.
Missing Link in Kidney Cancer Prognosis Identified
Dallas, TX — Normal cells located next to kidney cancer cells provide new clues about prognosis and survival rates, researchers from UT Southwestern Medical Center’s Kidney Cancer Program rep...
Researchers Discover How Colon Cancer Mutates to Escape the Immune System
Los Angeles, CA — A UCLA-led study has found how colon cancer alters its genes during development in order to avoid detection by the immune system, creating a specific genetic imprint in the proces...
Zebrafish Expose Tumour Pathway in Childhood Muscle Cancer
Dallas, TX — A popular aquarium fish may hold answers to how tumours form in a childhood cancer.
Childhood Cancer: The Four Survival Strategies of Tumour Cells
Lund, Sweden — Cancer cells in children tend to develop by following four main trajectories – and two of them are linked to relapse of the disease, research shows. The four strategies can occur...
Lipid Molecules can be Used for Cancer Growth
Stockholm, Sweden — Cancer cells can when the blood supply is low use lipid molecules as fuel instead of blood glucose. This has been shown in animal tumour models by researchers at Karolinska Institutet...
Scientists Reveal Likely Cause of Childhood Leukaemia
London, UK — A major new analysis reveals for the first time the likely cause of most cases of childhood leukaemia, following more than a century of controversy about its origins.
Resetting the Epigenetic Balance for Cancer Therapy
Evanston, IL — Though mutations in a gene called MLL3 are common across many types of cancers, their relationship to the development of the disease has been unclear.
New Data Changes the Way Scientists Explain How Cancer Tumours Develop
Galveston, Texas (Sciasts) — A collaborative research team has uncovered new information that more accurately explains how cancerous tumours grow within the body.
Research Suggests Enzyme’s Movement May Be Key to New Cancer Drugs
Tucson, AZ — Revealing all the steps required to activate an enzyme called a protein kinase may identify new ways to target cancer, according to new University of Arizona-led research.
Genetic Fixer-Uppers May Help Predict Bladder Cancer Prognosis
Hershey, PA — Mutations in genes that help repair damage to DNA may aid in predicting the prognosis of patients with bladder and other related cancers, according to researchers.
Depleted Metabolic Enzymes Promote Tumour Growth in Kidney Cancer
Philadelphia, PA — Kidney cancer, one of the ten most prevalent malignancies in the world, has increased in incidence over the last decade, likely due to rising obesity rates.
Tracing the Footprints of a Tumour: Genomic ‘Scars’ Allow Cancer Profiling
Vienna, Austria — When a cell develops into a tumour, something has gone terribly wrong: the uncontrolled growth, invasion of nearby tissues and finally metastasis are the result of many consecutive...
Study Links Breast Cancer to the Body’s Internal Clock
College Station, TX — For years, doctors have associated the BRCA1 and BRCA2 gene mutations with an increased risk of breast cancer.
Study Discovers New Molecular Mechanism Likely Involved in Cancer Metastasis
Baltimore, MD — Scientists knew the PDK1 signaling pathway was active in metastasizing cancer cells, but no one knew why. New research has identified a critical function of the PDK1 pathway, creating...
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