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New Signalling Pathway could Shed Light on Damage Repair During Brain Injury

July 8, 2021
Mindzilla

Plymouth, UK — Most human cells are able to repair damage by dividing at wounds. But mature nerve cells (neurons) in our brain are different. If they attempt division, they will likely die –...

Self-Excising Designer Proteins Report Isoform Expression

June 8, 2021
Mindzilla

Munich, Germany — Proteins are the key players in our cellular processes. Their generation follows principles called transcription and translation. First, DNA copies its genetic information to messenger...

Chaperone Protein Imbalance Promotes Toxic Tau Buildup in Ageing Brain

April 21, 2021
Mindzilla

Tampa, FL — Chaperone protein imbalance can play a significant role in initiating toxic accumulation of tau in the ageing brain – an early step in the development of Alzheimer’s disease...

How Tangled Proteins Kill Brain Cells, Promote Alzheimer’s, CTE

April 19, 2021
Mindzilla

Boulder, CO — Look deep inside the brain of someone with Alzheimer’s disease, most forms of dementia or the concussion-related syndrome known as chronic traumatic encephalopathy (CTE) and you’ll...

Researchers Discover New Way to Monitor & Prevent Nerve Cell Deterioration After TBI

April 14, 2021
Mindzilla

Cleveland, OH — Violent blows or jolts to the head can cause traumatic brain injury (TBI), and there are currently about five million people in the U.S. living with some form of chronic impairment...

Automated Imaging Detects and Tracks Brain Protein Involved in Alzheimer’s Disease

February 3, 2021
Mindzilla

Boston, MA — Amyloid-beta and tau are the two key abnormal protein deposits that accumulate in the brain during the development of Alzheimer’s disease, and detecting their buildup at an early...

Automated Imaging Reveals Where TAU Protein Originates in the Brain in Alzheimer’s Disease

January 21, 2021
Mindzilla

Washington, DC — Researchers have developed an automated method that can track the development of harmful clumps of TAU protein related to Alzheimer’s disease in the brain, according to work...

Researchers Discover a Rare Genetic Form of Dementia

October 5, 2020
Mindzilla

Philadelphia, PA — A new, rare genetic form of dementia has been discovered by a team of Penn Medicine researchers. This discovery also sheds light on a new pathway that leads to protein build up in...

Unlocking the Mystery of Tau for Treatment of Neurodegenerative Diseases

September 10, 2020
Mindzilla

Nagoya, Japan — Frontotemporal lobar degeneration (FTLD) is a type of dementia that appears earlier in life than Alzheimer’s disease (AD). Both FTLD and AD, along with several other neurodegenerative...

Plasticity may Make Neurons Vulnerable to Alzheimer’s Disease

June 30, 2020
Mindzilla

New York, NY — Neurons that regularly remodel are more prone to Alzheimer’s disease and die when that remodeling goes awry, a new study suggests. The work is the first to track the progression...

Could Targeting Alzheimer’s-Associated Protein Prevent Autism?

March 3, 2020
Mindzilla

San Francisco, CA — Autism manifests in myriad forms. Symptoms and severity vary from person to person, but all autism spectrum disorders share three core symptoms: impaired social interactions, communication...

Tau-Mediated RNA Splicing Errors Linked to Alzheimer’s Disease

October 8, 2019
Mindzilla

Houston, TX — A collaborative study published today in the journal Cell Reports provides evidence for a new molecular cause for neurodegeneration in Alzheimer’s disease. The study, led by researchers...

Tracking Alzheimer’s Disease Pathology in Single Neuronal Cells

September 26, 2019
Mindzilla

Coventry, UK — University of Warwick researchers have developed a superior method to describe the very earliest effects that Alzheimer’s Disease proteins have on the properties of brain cells. In...

Hidden Differences Between Pathology of CTE and Alzheimer’s Disease, Researchers Discover

March 21, 2019
Mindzilla

Bloomington, IN — An international team of scientists at Indiana University School of Medicine, University of Kansas and the U.K. Medical Research Council have dismantled the belief that Alzheimer’s...

Untangling Tau: Researchers Find a ‘Druggable Target’ for Treating Alzheimer’s Disease

January 25, 2019
Mindzilla

San Diego, CA — The accumulation of amyloid beta (Aβ) plaques and tangles of a protein called tau in the brain are hallmarks of Alzheimer’s disease (AD). Much effort has focused on the former,...

One Type of Brain Cell May Invite Alzheimer’s, Says Study

December 19, 2018
Mindzilla

Columbus, OH — Better tactics for detecting, preventing and treating Alzheimer’s disease depend on a clearer understanding of cellular-level changes in the minds of patients, and a new study has uncovered...

Neurons with Good Housekeeping are Protected from Alzheimer’s

December 17, 2018
Mindzilla

New York, NY — Some neurons in the brain protect themselves from Alzheimer’s with a cellular cleaning system that sweeps away toxic proteins associated with the disease, according to a new study...

Researcher Identifies Promising Diagnostic Tool for Alzheimer’s Disease

December 10, 2018
Mindzilla

Baltimore, MD — Researchers at Johns Hopkins Medicine have identified in live human brains new radioactive “tracer” molecules that bind to and “light up” tau tangles, a protein...

Alzheimer’s-Associated Tau Protein Disrupts Molecular Transport within Neurons

September 6, 2018
Mindzilla

Boston, MA — A multi-institutional study led by investigators at Massachusetts General Hospital (MGH) and Johns Hopkins School of Medicine has found how the abnormal form of tau that accumulates in...

Secret Sulfate Code that Lets Bad Tau In

July 16, 2018
Mindzilla

Dallas, TX — Researchers have uncovered details of how cells invite inside corrupted proteins that can turn normal proteins corrupt, leading to neurodegenerative diseases such as Alzheimer’s and...

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